Associate professor Ethan Scott and Dr. Lena Constantin recently carried out a study using zebrafish that carry the same genetic mutations as humans with “Fragile X” syndrome and autism. During their research, they discovered the neural networks and pathways that produce hypersensitivities to sound in both zebrafish and humans.
What is Fragile X syndrome?
Fragile X syndrome (commonly referred to as FXS) is a genetic disorder caused by changes in a gene that scientists call the “fragile X mental retardation 1 (FMR1)” gene. This gene typically makes a protein called fragile X mental retardation protein (FMRP) that’s needed for typical brain development. The brains of people with FXS do not make this protein, and if it is there, it’s abnormal.
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