Why Do Proteins Misfold? The Answer Could Point to Parkinson’s Disease Therapies – Technology Networks

Photomicrographs of regions of substantia nigra in this Parkinson’s patient show Lewy bodies and Lewy neurites in various magnifications. Lewy bodies are protein clumps consisting of alpha-synuclein and other associated proteins. Credit: Suraj Rajan / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0)


A group of researchers have identified identified a link between the structure of the disease-linked protein alpha-synuclein and its potential to aggregate and misfold.

Alpha-synuclein aggregates are the hallmark of neurodegenerative disorders, such as Parkinson’s disease. Their findings, published today in Nature Communications, identify potential new therapeutic targets in the treatment of Parkinson’s disease.

Click here to read full article https://www.technologynetworks.com/neuroscience/news/why-do-proteins-misfold-the-answer-could-point-to-parkinsons-disease-therapies-335807

Font Resize