Study reveals neural mechanisms underlying state mental fatigue in multiple sclerosis – News-Medical.Net

Researchers at Kessler Foundation conducted a pilot study comparing the effects of mental fatigue on brain activation patterns in people with and without multiple sclerosis (MS). Their findings indicate significant differences between the two groups in their recruitment of neural resources in response to increased task demands.

The article, “Neural mechanisms underlying state mental fatigue in multiple sclerosis: A pilot study,” was published in the Journal of Neurology on April 29, 2020. (Doi: 10.1007/s00415-09853-w) The authors are Michelle H. Chen, PhD, Glenn Wylie, DPhil, Rosalia Dacosta-Aguayo, PhD, John DeLuca, PhD, and Helen Genova, PhD, of Kessler Foundation, and Brian M. Sandroff, PhD, of the University of Alabama at Birmingham.

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