A new paper by OpenLab Gene and Cell Technology saw light in International Journal of Molecular Sciences.
“Spinal cord injury is a serious problem which can lead to a significant reduction in the patient’s quality of life. After trauma, many biochemical reactions and cell-to-cell interactions are activated, the results of which determine the possibility of nerve tissue repair and preservation of its functions. The most important participants of these processes are microglia cells—immune cells of the central nervous system,” explains Junior Research Associate Elvira Akhmetzyanova.
Employees of the laboratory studied the behavior of microglia cells under conditions of in vitro modeling of spinal cord injury of different severity in various posttraumatic periods (acute, subacute and chronic). It was found for the first time that cells of the brain immune system play a significant role in the processes of inflammation and recovery in severe spinal cord injury.