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  • Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss – National Institutes of Health

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss – National Institutes of Health

Tuesday, 27 July, 2021

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss – National Institutes of Health

Light enters the front of the eye and reaches the retina. Photoreceptors at the back of the retina convert light into signals and sends them to bipolar and retinal ganglion cells. Axons from retinal ganglion cells form the optic nerve, which carries signals from the eye to regions of the brain that process vision. National Eye Institute

 
A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness. The report was published in Cell.

Glaucoma results from irreversible neurodegeneration of the optic nerve, the bundle of axons from retinal ganglion cells that transmits signals from the eye to the brain to produce vision. Available therapies slow vision loss by lowering elevated eye pressure, however some glaucoma progresses to blindness despite normal eye pressure. Neuroprotective therapies would be a leap forward, meeting the needs of patients who lack treatment options.

Read more at: https://www.nih.gov/news-events/news-releases/scientists-discover-gene-therapy-provides-neuroprotection-prevent-glaucoma-vision-loss

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