Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries – News-Medical.Net

Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine.

The researchers were also able to identify the underlying genetic mechanism by which LDH works. This understanding should allow further modification of the therapy which, in combination with other elements, could finally produce a comprehensive, clinically applicable system for spinal cord injury relief in humans.

The research appears in the American Chemical Society journal ACS Nano on February 2.

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