Predictive models could provide more accurate detection of early-stage Parkinson’s disease – Medical Xpress

Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia

 

How is your sense of smell? Do you find yourself frequently dozing off during the day or thrashing about during dreams? Often, early stage Parkinson’s disease does not present with typical motor disturbance symptoms, making diagnosis problematic. Now, neuroscientists at York University have found five different models that use these types of non-motor clinical as well as biological variables to more accurately predict early-stage Parkinson’s disease.

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