Using advanced diffusion-weighted imaging, Kessler Foundation researchers investigated the relationship between rate of cognitive fatigue and microstructural changes in the brains of persons with multiple sclerosis (MS). Their findings help to fill a gap in the current literature by associating microstructural white matter (i.e., tracts that send signals within the brain) and basal ganglia (i.e., structures deep within the brain that have been linked to fatigue in neurological populations, including MS) with changes to the rate in which persons with MS fatigue over time.
Their findings were reported in Frontiers in Neurology on July 04, 2022, in the open access article entitled “Associations of White Matter and Basal Ganglia Microstructure to Cognitive Fatigue Rate in Multiple Sclerosis,” (doi: 10.3389/fneur.2022.911012). The authors are Cristina Román, PhD, Glenn Wylie, DPhil, John DeLuca, PhD, and Brian Yao, PhD.
Read more at: https://kesslerfoundation.org/press-release/new-study-advances-knowledge-role-brain-pathology-and-cognitive-fatigue-multiple
