A computational model of how Parkinson’s disease evolves over time may help guide physicians in tailoring levodopa doses to a patient’s needs at given disease stages.
Levodopa works to ease the slowness or difficulty in moving, known as bradykinesia, experienced by many people with Parkinson’s. But its effectiveness wanes as the disease progresses and adjustments are needed. Yet too high a dose can cause the uncontrollable, jerky movements known as dyskinesia.
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