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By Disabled People for Disabled People

Thursday, 23 March, 2023

New Insights into Origins of Spinal Muscular Atrophy — Mirage News

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

The discovery suggests a new way to treat SMA-a devastating childhood motor neuron disease that affects 1 in 6,000 children. In the most severe cases, and when left untreated, children born with SMA die within the first two years of life.

The researchers also used their finding to develop an experimental therapy that improved survival in mice with severe SMA by 30-fold, one of the greatest increases seen with any treatment in mouse models of SMA.

Read more at: https://www.miragenews.com/new-insights-into-origins-of-spinal-muscular-971364/

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