Researchers at the University of Zurich and Munich’s LMU Klinikum hospital have studied the immune system of pairs of monozygotic twins to identify the influence of the environment and of genetics in cases of multiple sclerosis. In the process, they may have discovered precursor cells of the disease-causing T cells.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and the most common cause of neurological impairment in young adults. In MS, the patient’s own immune system attacks the brain and spinal cord, resulting in cumulative neurological deficits such as damaged sight, sensory disturbances, motor deficits (e.g. limiting the ability to walk) as well as cognitive impairment. Although the cause of MS is still unclear, a variety of genetic risk factors and environmental influences have already been linked to the disease.
Read more at: https://www.media.uzh.ch/en/Press-Releases/2022/twins.html