Mouse study shows lab-grown, self-sustainable muscle cells could repair diseases such as muscular dystrophy – Drug Target Review

A new study highlights how scientists have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, findings that could lead to therapeutics to treat muscular dystrophy disorder.

Scientists from John Hopkins Medicine, US, have successfully developed human muscle stem cells able of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscular dystrophy patients. The findings were recently published in Cell Stem Cell.

To make the self-renewing stem cells, the scientists began with laboratory-grown human skin cells that were genetically reprogrammed to a more primitive state in which the cells have the potential to become almost any type of cell in the body. At this point, the cells are known as induced pluripotent stem cells (iPSC), and they are mixed with a solution of standard cell growth factors and nutrients that nudge them to differentiate into specific cell types.

Read more at: https://www.drugtargetreview.com/news/103088/mouse-study-shows-lab-grown-self-sustainable-muscle-cells-could-repair-diseases-such-as-muscular-dystrophy/