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  • Dominant form of heart failure caused by metabolic-immune interaction, review article suggests – UT Southwestern Medical Center

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests – UT Southwestern Medical Center

Thursday, 24 March, 2022

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests – UT Southwestern Medical Center

Joseph Hill, M.D., Ph.D.

 
The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues. The article, published in Nature Cardiovascular Research, argues for more research into this root cause to develop truly effective treatments.
“Heart failure with preserved ejection fraction affects millions of people around the globe, but we currently have little to offer these patients because the mechanisms behind it have been unknown. It’s been called the single greatest unmet need in cardiovascular medicine,” said the article’s senior author Joseph Hill, M.D., Ph.D., Professor of Internal Medicine and Molecular Biology and Chief of Cardiology at UT Southwestern. “We now have insight into this condition that we didn’t have even five years ago, observations that could lead to viable clinical targets.”
Read more at: https://www.utsouthwestern.edu/newsroom/articles/year-2022/dominant-form-of-heart-failure.html

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