Researchers in Germany say they cannot rule out a small risk for key symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in children who had a COVID-19 infection.
In a cross-sectional study involving more than 600 children, a crude analysis found that clustered ME/CFS symptoms were more frequently reported in those with SARS-CoV-2 seropositivity compared to those who were seronegative (40.0% vs 29.6%; risk ratio [RR] 1.35 95% CI 1.03-1.78), according to Anna-Lisa Sorg, MSc, of Ludwig-Maximilians-University Munich, and colleagues.
However, after adjusting for sex, age, and pre-existing disease, the association was smaller and no longer statistically significant (adjusted RR 1.18, 95% CI 0.90-1.53), as shown in the team’s study in JAMA Network.
Read more at: https://www.medpagetoday.com/infectiousdisease/covid19/100938