Researchers at Boston Children’s Hospital and the Broad Institute of MIT and Harvard recently took a step toward a future where hereditary deafness could be corrected with a single injection into the ear. They used a super-precise type of gene editing to temporarily improve hearing in deaf lab mice.
The technique, known as base editing — sometimes called CRISPR 2.0 — allowed them to repair a mutation in the TMC1 gene. Babies who inherit this mutation from both parents lose their hearing at just four weeks old.
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